Mankhwala oletsa thovu amagwiritsidwa ntchito kuchepetsa mphamvu ya pamwamba pa madzi, yankho ndi choyimitsa, kupewa kupangika kwa thovu, kapena kuchepetsa thovu lomwe limapangika panthawi yopanga mafakitale. Mankhwala oletsa thovu omwe amagwiritsidwa ntchito kwambiri ndi awa:

I. Mafuta achilengedwe (monga Mafuta a Soya, Mafuta a Chimanga, ndi zina zotero)

Ubwino: zomwe zilipo, zotsika mtengo komanso zosavuta kugwiritsa ntchito;

Zoyipa: n'zosavuta kuwonongeka ndikuwonjezera asidi ngati sizisungidwa bwino.

II.Mowa Wambiri wa Carbon

Mowa wambiri wa kaboni ndi molekyulu yolunjika yokhala ndi hydrofobicity yamphamvu komanso hydrophilicity yofooka, yomwe ndi antifoamer yothandiza m'madzi. Mphamvu ya mowa yoletsa thovu imakhudzana ndi kusungunuka kwake ndi kufalikira kwake mu yankho la thovu. Mowa wa C7 ~ C9 ndiye Antifoamers yothandiza kwambiri. Mowa wambiri wa kaboni wa C12 ~ C22 umakonzedwa ndi ma emulsifiers oyenera okhala ndi kukula kwa tinthu tating'onoting'ono ta 4 ~ 9μm, okhala ndi emulsion yamadzi ya 20~50%, kutanthauza, defoamer m'madzi. Ma esters ena amakhalanso ndi mphamvu yoletsa thovu mu penicillin fermentation, monga phenylethanol oleate ndi lauryl phenylacetate.

III.Zoletsa Thovu za Polyether

1. Zotsukira Malupanga a GP

Yopangidwa powonjezera polymerization ya propylene oxide, kapena chisakanizo cha ethylene oxide ndi propylene oxide, ndi glycerol ngati choyambira. Ili ndi hydrophilicity yochepa komanso kusungunuka kochepa mu thovu, kotero ndiyoyenera kugwiritsidwa ntchito mu madzi opyapyala. Popeza mphamvu yake yoletsa thovu ndi yapamwamba kuposa ya defoaming, ndiyoyenera kuwonjezeredwa mu basal medium kuti ilepheretse njira yonse yopangira thovu.

2. Zoletsa Thovu za GPE

Ethylene oxide imawonjezedwa kumapeto kwa unyolo wa polypropylene glycol wa GP Antifoamers kuti ipange polyoxyethylene oxypropylene glycerol yokhala ndi hydrophilic end. GPE Antifoamer ili ndi hydrophilicity yabwino, mphamvu yamphamvu yoletsa thovu, komanso imasungunuka kwambiri zomwe zimapangitsa kuti ntchito yoletsa thovu ikhale yochepa. Chifukwa chake, imakhala ndi zotsatira zabwino mu msuzi wokhuthala.

3. Zoletsa Thovu za GPE

Copolymer ya block yokhala ndi unyolo wothira madzi kumapeto onse awiri ndi unyolo wothira madzi imapangidwa potseka kumapeto kwa unyolo wa GPE Antifoamers ndi hydrophobic stearate. Mamolekyu okhala ndi kapangidwe kameneka nthawi zambiri amasonkhana pamalo olumikizirana ndi gasi ndi madzi, kotero amakhala ndi ntchito yamphamvu pamwamba komanso mphamvu yayikulu yochotsera madzi.

IV.Silikoni Yosinthidwa ya Polyether

Ma Silicone Oletsa Kutupa a Polyether Modified ndi mtundu watsopano wa ma defoamer amphamvu kwambiri. Ndi otsika mtengo chifukwa cha ubwino wake wofalikira bwino, mphamvu yoletsa thovu mwamphamvu, kukhazikika, osati poizoni komanso osavulaza, kusinthasintha kochepa komanso mphamvu yolimba ya ma Antifoamer. Malinga ndi njira zosiyanasiyana zolumikizira mkati, zitha kugawidwa m'magulu awiri otsatirawa:

1. Copolymer yokhala ndi -Si-OC- bond yokonzedwa ndi asidi ngati chothandizira. Defoamer iyi ndi yosavuta kusungunuka ndipo ili ndi kukhazikika kofooka. Ngati pali amine buffer, imatha kusungidwa kwa nthawi yayitali. Koma chifukwa cha mtengo wake wotsika, kuthekera kwa chitukuko n'kodziwikiratu.

2. Copolymer yolumikizidwa ndi – si-c-bond ili ndi kapangidwe kokhazikika ndipo imatha kusungidwa kwa zaka zoposa ziwiri pansi pa mikhalidwe yotsekedwa. Komabe, chifukwa cha kugwiritsa ntchito platinamu yokwera mtengo ngati chothandizira popanga, mtengo wopangira wa mitundu iyi ya antifoamers ndi wokwera, kotero sunagwiritsidwe ntchito kwambiri.

V. Chotsukira thovu cha Silicon chachilengedwe

...mutu wotsatira.