Diphenylcarbodiimide, mokhoa oa lik'hemik'hale2162-74-5, ke motsoako o hohetseng tlhokomelo e pharaletseng lefapheng la k'hemistri ea lintho tse phelang. Morero oa sengoloa sena ke ho fana ka kakaretso ea diphenylcarbodiimide, thepa ea eona, ts'ebeliso le bohlokoa ba eona lits'ebetsong tse fapaneng.

Diphenylcarbodiimide ke motsoako o nang le foromo ea limolek'hule ea C13H10N2. E tšoeu ho isa ho e tšoeu, e qhibilihang hanyane ka metsing, e qhibilihang habonolo ka har'a acetone, ethanol, chloroform le li-solvents tse ling tsa tlhaho. Motsoako ona o tsebahala haholo ka bokhoni ba oona ba ho sebetsa e le reagent e feto-fetohang ho etseng lintho tse phelang, haholo-holo ho thehoeng ha li-amide le urea.

E 'ngoe ea litšobotsi tsa bohlokoa tsa diphenylcarbodiimide ke ho sebetsa ha eona ka li-amine le li-carboxylic acid, e leng se lebisang ho thehoeng ha li-amides. Karabelo ena e bitsoa karabelo ea ho kopanya li-carbodiimide 'me e sebelisoa haholo ho etseng li-peptide le phetohong ea limolek'hule. Ho phaella moo, diphenylcarbodiimide e ka sebetsana le li-alcohols ho etsa polyurethane, e leng se etsang hore e be reagent ea bohlokoa tlhahisong ea thepa ea polyurethane.

Indastering ea meriana, diphenylcarbodiimide e ka sebelisoa ho kopanya meriana e fapaneng le metsoako e sebetsanang le meriana. Bokhoni ba eona ba ho khothaletsa ho thehoa ha maqhama a amide bo bohlokoa haholo bakeng sa nts'etsopele ea meriana ea peptide le li-bioconjugates. Ho feta moo, karabelo ea motsoako ho li-carboxylic acid e etsa hore e be sesebelisoa se molemo sa ho kopanya meriana le limolek'hule tse shebaneng, ka hona ho nolofalletsa moralo oa litsamaiso tsa ho fana ka meriana tse shebaneng.

Ntle le karolo ea tsona tlhahisong ea lintho tse phelang, diphenylcarbodiimides li ithutiloe bakeng sa tšebeliso ea tsona e ka bang teng saenseng ea thepa. Karabelo ea motsoako ona ho alcohols e etsa hore e be molemo tlhahisong ea foam ea polyurethane, liphahlo le likhomaretsi. Bokhoni ba eona ba ho etsa polyurethane bo e etsa hore e be motsoako oa bohlokoa tlhahisong ea thepa ea polyurethane e tšoarellang, e feto-fetohang e sebelisoang liindastering tse fapaneng ho tloha kahong ho ea likoloing.

Bohlokoa ba diphenylcarbodiimides bo atoloha ho ya masimong a bioconjugation le khemistri ya bioorthogonal. Karabelo ya yona mabapi le dimolekule e sebedisitswe bakeng sa phetoho e ikgethang ya diprotheine le di-nucleic acid sebakeng se itseng, e leng se nolofalletsang ntshetsopele ya di-bioconjugate tse ntjha le di-probe tsa bioimaging. Ho feta moo, ho tsamaellana ha motsoako le ditikoloho tse metsi ho etsa hore e be sesebediswa sa bohlokwa bakeng sa ho ntshetsa pele dikarabelo tsa bioorthogonal ho ithuta ditshebetso tsa baeloji ditsamaisong tse phelang.

Ka bokhutšoanyane, diphenylcarbodiimide, foromo ea lik'hemik'hale 2162-74-5, ke motsoako o sebetsang ka bongata o nang le lits'ebetso tse fapaneng masimong a tlhahiso ea lintho tse phelang, meriana, saense ea thepa, le k'hemistri e kopantsoeng le lintho tse phelang. Karabelo ea eona mabapi le li-amine, li-carboxylic acid, le lino tse tahang e etsa hore e be sesebelisoa sa bohlokoa bakeng sa ho thehoa ha li-amides, li-carbamate le li-bioconjugates. Ha lipatlisiso libakeng tsena li ntse li tsoela pele, li-diphenylcarbodiimides li ka lula li le libapali tsa bohlokoa ntlafatsong ea thepa e ncha le metsoako e sebetsang ea lintho tse phelang, e tlatsetsang tsoelo-peleng masimong a fapaneng a saense le a indasteri.